| Lab Diamond | Natural Diamond | |
| Durability | 10 on the Mohs scale | 10 on the Mohs scale |
| Brilliance | Refractive index ranges from 2.417 to 2.419 | Refractive index ranges from 2.417 to 2.419 |
| Color | Primarly colorless, but can also occur in many color options that are often more vivid than natural options | Primarly colorless, but can also occur in many color options including pink, blue, and yellow |
| Grading | Graded on cut, color, clarity, and carat | Graded on cut, color, clarity, and carat |
| Certification | Certified by reputable gemological institutions | Certified by reputable gemological institutions |
| Origin | Grown in controlled laboratories over several days to weeks, then cut and polished | Formed deep in Earth over billions of years, mined, cut, and polished |
| Rarity | Can be produced in increasing quantities as technology advances | Limited quantities based on geological conditions |
| Price | Lower cost due to availability | Higher cost due to mining and rarity |